YDL175C

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Systematic name YDL175C
Gene name AIR2
Aliases
Feature type ORF, Verified
Coordinates Chr IV:145519..144485
Primary SGDID S000002334


Description of YDL175C: zinc knuckle protein, involved in nuclear RNA quality control as a component of the TRAMP complex; stimulates the poly(A)polymerase activity of Pap2p in vitro; functionally redundant with Air1p[1][2][3][4]




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References

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  1. Inoue K, et al. (2000) Novel RING finger proteins, Air1p and Air2p, interact with Hmt1p and inhibit the arginine methylation of Npl3p. J Biol Chem 275(42):32793-9 SGD PMID 10896665
  2. Vanacova S, et al. (2005) A new yeast poly(A) polymerase complex involved in RNA quality control. PLoS Biol 3(6):e189 SGD PMID 15828860
  3. LaCava J, et al. (2005) RNA degradation by the exosome is promoted by a nuclear polyadenylation complex. Cell 121(5):713-24 SGD PMID 15935758
  4. Wyers F, et al. (2005) Cryptic pol II transcripts are degraded by a nuclear quality control pathway involving a new poly(A) polymerase. Cell 121(5):725-37 SGD PMID 15935759

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