YCL008C

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Systematic name YCL008C
Gene name STP22
Aliases VPS23
Feature type ORF, Verified
Coordinates Chr III:106853..105696
Primary SGDID S000000514


Description of YCL008C: Component of the ESCRT-I complex, which is involved in ubiquitin-dependent sorting of proteins into the endosome; homologous to the mouse and human Tsg101 tumor susceptibility gene; mutants exhibit a Class E Vps phenotype[1][2]




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References

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  1. Babst M, et al. (2000) Mammalian tumor susceptibility gene 101 (TSG101) and the yeast homologue, Vps23p, both function in late endosomal trafficking. Traffic 1(3):248-58 SGD PMID 11208108
  2. Katzmann DJ, et al. (2001) Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I. Cell 106(2):145-55 SGD PMID 11511343

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