YOL076W

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Systematic name YOL076W
Gene name MDM20
Aliases DEC1
Feature type ORF, Verified
Coordinates Chr XV:187024..189414
Primary SGDID S000005436


Description of YOL076W: Non-catalytic subunit of the NatB N-terminal acetyltransferase, which catalyzes acetylation of the amino-terminal methionine residues of all proteins beginning with Met-Asp or Met-Glu and of some proteins beginning with Met-Asn or Met-Met; involved in mitochondrial inheritance and actin assembly[1][2]




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References

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  1. Polevoda B, et al. (2003) Nat3p and Mdm20p are required for function of yeast NatB Nalpha-terminal acetyltransferase and of actin and tropomyosin. J Biol Chem 278(33):30686-97 SGD PMID 12783868
  2. Singer JM and Shaw JM (2003) Mdm20 protein functions with Nat3 protein to acetylate Tpm1 protein and regulate tropomyosin-actin interactions in budding yeast. Proc Natl Acad Sci U S A 100(13):7644-9 SGD PMID 12808144

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