YDR457W

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Systematic name YDR457W
Gene name TOM1
Aliases
Feature type ORF, Verified
Coordinates Chr IV:1369783..1379589
Primary SGDID S000002865


Description of YDR457W: E3 ubiquitin ligase of the hect-domain class; has a role in mRNA export from the nucleus and may regulate transcriptional coactivators[1][2][3]




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References

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  1. Davey M, et al. (2000) The yeast peptidyl proline isomerases FPR3 and FPR4, in high copy numbers, suppress defects resulting from the absence of the E3 ubiquitin ligase TOM1. Mol Gen Genet 263(3):520-6 SGD PMID 10821187
  2. Saleh A, et al. (1998) TOM1p, a yeast hect-domain protein which mediates transcriptional regulation through the ADA/SAGA coactivator complexes. J Mol Biol 282(5):933-46 SGD PMID 9753545
  3. Duncan K, et al. (2000) A putative ubiquitin ligase required for efficient mRNA export differentially affects hnRNP transport. Curr Biol 10(12):687-96 SGD PMID 10873801

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