YDR335W
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| Systematic name | YDR335W |
| Gene name | MSN5 |
| Aliases | KAP142, STE21 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:1141163..1144837 |
| Primary SGDID | S000002743 |
Description of YDR335W: Karyopherin involved in nuclear import and export; shown to be responsible for nuclear import of replication protein A and for export of several proteins including Swi6p, Far1p, and Pho4p; cargo dissociation involves binding to RanGTP[1][2][3][4][5]
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References
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- ↑ Blondel M, et al. (1999) Nuclear export of Far1p in response to pheromones requires the export receptor Msn5p/Ste21p. Genes Dev 13(17):2284-300 SGD PMID 10485850
- ↑ Kaffman A, et al. (1998) The receptor Msn5 exports the phosphorylated transcription factor Pho4 out of the nucleus. Nature 396(6710):482-6 SGD PMID 9853758
- ↑ Alepuz PM, et al. (1999) The Saccharomyces cerevisiae RanGTP-binding protein msn5p is involved in different signal transduction pathways. Genetics 153(3):1219-31 SGD PMID 10545454
- ↑ Yoshida K and Blobel G (2001) The karyopherin Kap142p/Msn5p mediates nuclear import and nuclear export of different cargo proteins. J Cell Biol 152(4):729-40 SGD PMID 11266464
- ↑ Queralt E and Igual JC (2003) Cell cycle activation of the Swi6p transcription factor is linked to nucleocytoplasmic shuttling. Mol Cell Biol 23(9):3126-40 SGD PMID 12697814
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