YKR080W
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| Systematic name | YKR080W |
| Gene name | MTD1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XI:590037..590999 |
| Primary SGDID | S000001788 |
Description of YKR080W: NAD-dependent 5,10-methylenetetrahydrafolate dehydrogenase, plays a catalytic role in oxidation of cytoplasmic one-carbon units; expression is regulated by Bas1p and Bas2p, repressed by adenine, and may be induced by inositol and choline[1][2][3]
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References
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- ↑ West MG, et al. (1996) Metabolic role of cytoplasmic isozymes of 5,10-methylenetetrahydrofolate dehydrogenase in Saccharomyces cerevisiae. Biochemistry 35(9):3122-32 SGD PMID 8608153
- ↑ Denis V and Daignan-Fornier B (1998) Synthesis of glutamine, glycine and 10-formyl tetrahydrofolate is coregulated with purine biosynthesis in Saccharomyces cerevisiae. Mol Gen Genet 259(3):246-55 SGD PMID 9749667
- ↑ Santiago TC and Mamoun CB (2003) Genome expression analysis in yeast reveals novel transcriptional regulation by inositol and choline and new regulatory functions for Opi1p, Ino2p, and Ino4p. J Biol Chem 278(40):38723-30 SGD PMID 12871953
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