YKR029C

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Systematic name YKR029C
Gene name SET3
Aliases
Feature type ORF, Verified
Coordinates Chr XI:499475..497220
Primary SGDID S000001737


Description of YKR029C: Defining member of the SET3 histone deacetylase complex which is a meiosis-specific repressor of sporulation genes; necessary for efficient transcription by RNAPII; one of two yeast proteins that contains both SET and PHD domains[1][2][3]




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References

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  1. Pijnappel WW, et al. (2001) The S. cerevisiae SET3 complex includes two histone deacetylases, Hos2 and Hst1, and is a meiotic-specific repressor of the sporulation gene program. Genes Dev 15(22):2991-3004 SGD PMID 11711434
  2. Wang A, et al. (2002) Requirement of Hos2 histone deacetylase for gene activity in yeast. Science 298(5597):1412-4 SGD PMID 12434058
  3. Krogan NJ, et al. (2003) Methylation of histone H3 by Set2 in Saccharomyces cerevisiae is linked to transcriptional elongation by RNA polymerase II. Mol Cell Biol 23(12):4207-18 SGD PMID 12773564

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