YGL090W
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| Systematic name | YGL090W |
| Gene name | LIF1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:343322..344587 |
| Primary SGDID | S000003058 |
Description of YGL090W: Component of the DNA ligase IV complex that mediates nonhomologous end joining in DNA double-strand break repair; physically interacts with Dnl4p and Nej1p; homologous to mammalian XRCC4 protein[1][2][3]
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Contents
Community Commentary
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References
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- ↑ Deshpande RA and Wilson TE (2007) Modes of interaction among yeast Nej1, Lif1 and Dnl4 proteins and comparison to human XLF, XRCC4 and Lig4. DNA Repair (Amst) 6(10):1507-16 SGD PMID 17567543
- ↑ Teo SH and Jackson SP (2000) Lif1p targets the DNA ligase Lig4p to sites of DNA double-strand breaks. Curr Biol 10(3):165-8 SGD PMID 10679327
- ↑ Herrmann G, et al. (1998) Saccharomyces cerevisiae LIF1: a function involved in DNA double-strand break repair related to mammalian XRCC4. EMBO J 17(14):4188-98 SGD PMID 9670033
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