YER065C

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Systematic name YER065C
Gene name ICL1
Aliases
Feature type ORF, Verified
Coordinates Chr V:286912..285239
Primary SGDID S000000867


Description of YER065C: Isocitrate lyase, catalyzes the formation of succinate and glyoxylate from isocitrate, a key reaction of the glyoxylate cycle; expression of ICL1 is induced by growth on ethanol and repressed by growth on glucose[1][2]




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DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically higher expression in carbon limited chemostat cultures versus carbon excess. [3] [4]





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References

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  1. Luttik MA, et al. (2000) The Saccharomyces cerevisiae ICL2 gene encodes a mitochondrial 2-methylisocitrate lyase involved in propionyl-coenzyme A metabolism. J Bacteriol 182(24):7007-13 SGD PMID 11092862
  2. Fernandez E, et al. (1992) The ICL1 gene from Saccharomyces cerevisiae. Eur J Biochem 204(3):983-90 SGD PMID 1551398
  3. Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
  4. submitted by Viktor Boer on 2003-07-25

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