YBR279W
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Systematic name | YBR279W |
Gene name | PAF1 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr II:761253..762590 |
Primary SGDID | S000000483 |
Description of YBR279W: RNAP II-associated protein; defines large complex biochemically and functionally distinct from the Srb-Mediator form of Pol II holoenzyme; required for full expression of a subset of cell cycle-regulated genes; homolog of human PD2/hPAF1[1][2][3]
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References
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- ↑ Moniaux N, et al. (2006) The human homologue of the RNA polymerase II-associated factor 1 (hPaf1), localized on the 19q13 amplicon, is associated with tumorigenesis. Oncogene 25(23):3247-57 SGD PMID 16491129
- ↑ Betz JL, et al. (2002) Phenotypic analysis of Paf1/RNA polymerase II complex mutations reveals connections to cell cycle regulation, protein synthesis, and lipid and nucleic acid metabolism. Mol Genet Genomics 268(2):272-85 SGD PMID 12395202
- ↑ Mueller CL and Jaehning JA (2002) Ctr9, Rtf1, and Leo1 are components of the Paf1/RNA polymerase II complex. Mol Cell Biol 22(7):1971-80 SGD PMID 11884586
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