YPL092W
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| Systematic name | YPL092W | |
| Gene name | SSU1 | |
| Aliases | LPG16 | |
| Feature type | ORF, Verified | |
| Coordinates | Chr XVI:373790..375166 | |
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Description of YPL092W: Plasma membrane sulfite pump involved in sulfite metabolism and required for efficient sulfite efflux; major facilitator superfamily protein[1][2]
DNA and RNA Details
Other DNA and RNA Details
Other Topic: evolution
The SSU1-R allele, which confers sulfite resistance to yeast cells, is the product of a reciprocal translocation between chromosomes VIII and XVI due to unequal crossing-over mediated by microhomology between very short sequences on the 5' upstream regions of the SSU1 and ECM34 genes. We show that this translocation is only present in wine yeast strains, suggesting that the use for millennia of sulfite as a preservative in wine production could have favoured its selection. [3] [4]
Other Topic: expression
Specifically lower expression in sulfur limited chemostat cultures versus sulfur excess. [5] [6]
Contents
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DNA and RNA Details
Other DNA and RNA Details
Other Topic: evolution
The SSU1-R allele, which confers sulfite resistance to yeast cells, is the product of a reciprocal translocation between chromosomes VIII and XVI due to unequal crossing-over mediated by microhomology between very short sequences on the 5' upstream regions of the SSU1 and ECM34 genes. We show that this translocation is only present in wine yeast strains, suggesting that the use for millennia of sulfite as a preservative in wine production could have favoured its selection. [3] [4]
Other Topic: expression
Specifically lower expression in sulfur limited chemostat cultures versus sulfur excess. [5] [6]
References
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- ↑ Park H and Bakalinsky AT (2000) SSU1 mediates sulphite efflux in Saccharomyces cerevisiae. Yeast 16(10):881-8 SGD PMID 10870099
- ↑ Avram D and Bakalinsky AT (1997) SSU1 encodes a plasma membrane protein with a central role in a network of proteins conferring sulfite tolerance in Saccharomyces cerevisiae. J Bacteriol 179(18):5971-4 SGD PMID 9294463
- ↑ 3.0 3.1 Perez-Ortin JE, et al. (2002) Molecular characterization of a chromosomal rearrangement involved in the adaptive evolution of yeast strains. Genome Res 12(10):1533-9 SGD PMID 12368245
- ↑ 4.0 4.1 submitted by Jose E. Perez-Ortin on 2004-06-04
- ↑ 5.0 5.1 Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
- ↑ 6.0 6.1 submitted by Viktor Boer on 2003-07-25
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