YOR266W
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| Systematic name | YOR266W |
| Gene name | PNT1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:821022..822293 |
Description of YOR266W: Mitochondrial inner membrane protein involved in export of proteins from the mitochondrial matrix; overexpression of PNT1 confers resistance to the anti-Pneumocystis carinii drug pentamidine, and deletion confers increased sensitivity[1][2]
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Contents
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References
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- ↑ He S and Fox TD (1999) Mutations affecting a yeast mitochondrial inner membrane protein, pnt1p, block export of a mitochondrially synthesized fusion protein from the matrix. Mol Cell Biol 19(10):6598-607 SGD PMID 10490599
- ↑ Ludewig G and Staben C (1994) Characterization of the PNT1 pentamidine resistance gene of Saccharomyces cerevisiae. Antimicrob Agents Chemother 38(12):2850-6 SGD PMID 7695273
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