YOR212W

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Systematic name YOR212W
Gene name STE4
Aliases HMD2
Feature type ORF, Verified
Coordinates Chr XV:742911..744182


Description of YOR212W: G protein beta subunit, forms a dimer with Ste18p to activate the mating signaling pathway, forms a heterotrimer with Gpa1p and Ste18p to dampen signaling; may recruit Rho1p to the polarized growth site during mating; contains WD40 repeats[1][2]




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References

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  1. Bar EE, et al. (2003) Gbetagamma recruits Rho1 to the site of polarized growth during mating in budding yeast. J Biol Chem 278(24):21798-804 SGD PMID 12660244
  2. Whiteway M, et al. (1989) The STE4 and STE18 genes of yeast encode potential beta and gamma subunits of the mating factor receptor-coupled G protein. Cell 56(3):467-77 SGD PMID 2536595

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