YOR176W

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Systematic name YOR176W
Gene name HEM15
Aliases
Feature type ORF, Verified
Coordinates Chr XV:662402..663583
Primary SGDID S000005702


Description of YOR176W: Ferrochelatase, a mitochondrial inner membrane protein, catalyzes the insertion of ferrous iron into protoporphyrin IX, the eighth and final step in the heme biosynthetic pathway[1][2][3]




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References

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  1. Labbe-Bois R (1990) The ferrochelatase from Saccharomyces cerevisiae. Sequence, disruption, and expression of its structural gene HEM15. J Biol Chem 265(13):7278-83 SGD PMID 2185242
  2. Urban-Grimal D and Labbe-Bois R (1981) Genetic and biochemical characterization of mutants of Saccharomyces cerevisiae blocked in six different steps of heme biosynthesis. Mol Gen Genet 183(1):85-92 SGD PMID 7035824
  3. Camadro JM and Labbe P (1988) Purification and properties of ferrochelatase from the yeast Saccharomyces cerevisiae. Evidence for a precursor form of the protein. J Biol Chem 263(24):11675-82 SGD PMID 3042776

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