YOL051W

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Systematic name YOL051W
Gene name GAL11
Aliases ABE1, MED15, RAR3, SDS4, SPT13
Feature type ORF, Verified
Coordinates Chr XV:234939..238184
Primary SGDID S000005411


Description of YOL051W: Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; affects transcription by acting as target of activators and repressors[1][2][3][4]




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References

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  1. Myers LC and Kornberg RD (2000) Mediator of transcriptional regulation. Annu Rev Biochem 69:729-49 SGD PMID 10966474
  2. Mizuno T and Harashima S (2003) Gal11 is a general activator of basal transcription, whose activity is regulated by the general repressor Sin4 in yeast. Mol Genet Genomics 269(1):68-77 SGD PMID 12715155
  3. Han SJ, et al. (2001) Med9/Cse2 and Gal11 modules are required for transcriptional repression of distinct group of genes. J Biol Chem 276(40):37020-6 SGD PMID 11470794
  4. Li Y, et al. (1995) Yeast global transcriptional regulators Sin4 and Rgr1 are components of mediator complex/RNA polymerase II holoenzyme. Proc Natl Acad Sci U S A 92(24):10864-8 SGD PMID 7479899

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