YNL262W

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Systematic name YNL262W
Gene name POL2
Aliases DUN2
Feature type ORF, Verified
Coordinates Chr XIV:148213..154881
Primary SGDID S000005206


Description of YNL262W: Catalytic subunit of DNA polymerase (II) epsilon, a chromosomal DNA replication polymerase that exhibits processivity and proofreading exonuclease activity; also involved in DNA synthesis during DNA repair; interacts extensively with Mrc1p[1][2][3]




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References

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  1. Lou H, et al. (2008) Mrc1 and DNA polymerase epsilon function together in linking DNA replication and the S phase checkpoint. Mol Cell 32(1):106-17 SGD PMID 18851837
  2. Shimizu K, et al. (2002) Fidelity of DNA polymerase epsilon holoenzyme from budding yeast Saccharomyces cerevisiae. J Biol Chem 277(40):37422-9 SGD PMID 12124389
  3. Burgers PM (1998) Eukaryotic DNA polymerases in DNA replication and DNA repair. Chromosoma 107(4):218-27 SGD PMID 9745046

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