YLL042C

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Systematic name YLL042C
Gene name ATG10
Aliases APG10
Feature type ORF, Verified
Coordinates Chr XII:52589..52086
Primary SGDID S000003965


Description of YLL042C: Conserved E2-like conjugating enzyme that mediates formation of the Atg12p-Atg5p conjugate, which is a critical step in autophagy[1][2][3]




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References

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  1. Meijer WH, et al. (2007) ATG genes involved in non-selective autophagy are conserved from yeast to man, but the selective Cvt and pexophagy pathways also require organism-specific genes. Autophagy 3(2):106-16 SGD PMID 17204848
  2. Tsukada M and Ohsumi Y (1993) Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett 333(1-2):169-74 SGD PMID 8224160
  3. Shintani T, et al. (1999) Apg10p, a novel protein-conjugating enzyme essential for autophagy in yeast. EMBO J 18(19):5234-41 SGD PMID 10508157

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