YGL037C
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| Systematic name | YGL037C |
| Gene name | PNC1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:427953..427303 |
| Primary SGDID | S000003005 |
Description of YGL037C: Nicotinamidase that converts nicotinamide to nicotinic acid as part of the NAD(+) salvage pathway, required for life span extension by calorie restriction; PNC1 expression responds to all known stimuli that extend replicative life span[1][2]
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References
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- ↑ Ghislain M, et al. (2002) Identification and functional analysis of the Saccharomyces cerevisiae nicotinamidase gene, PNC1. Yeast 19(3):215-24 SGD PMID 11816029
- ↑ Anderson RM, et al. (2003) Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae. Nature 423(6936):181-5 SGD PMID 12736687
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