YKR069W

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Systematic name YKR069W
Gene name MET1
Aliases MET20
Feature type ORF, Verified
Coordinates Chr XI:571254..573035
Primary SGDID S000001777


Description of YKR069W: S-adenosyl-L-methionine uroporphyrinogen III transmethylase, involved in the biosynthesis of siroheme, a prosthetic group used by sulfite reductase; required for sulfate assimilation and methionine biosynthesis[1][2][3]




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Community Commentary

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DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically higher expression in sulfur limited chemostat cultures versus sulfur excess. [4] [5]





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References

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  1. Thomas D, et al. (1992) Physiological analysis of mutants of Saccharomyces cerevisiae impaired in sulphate assimilation. J Gen Microbiol 138(10):2021-8 SGD PMID 1479340
  2. Hansen J, et al. (1997) Siroheme biosynthesis in Saccharomyces cerevisiae requires the products of both the MET1 and MET8 genes. FEBS Lett 401(1):20-4 SGD PMID 9003798
  3. Raux E, et al. (1999) The role of Saccharomyces cerevisiae Met1p and Met8p in sirohaem and cobalamin biosynthesis. Biochem J 338 ( Pt 3)():701-8 SGD PMID 10051442
  4. Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
  5. submitted by Viktor Boer on 2003-07-25

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