YBR179C
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| Systematic name | YBR179C |
| Gene name | FZO1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr II:589109..586542 |
| Primary SGDID | S000000383 |
Description of YBR179C: Mitofusin, mitochondrial integral membrane protein involved in mitochondrial fusion and mitochondrial genome maintenance; contains N-terminal GTPase domain; targeted for destruction by cytosolic components of the ubiquitin-proteasome system[1][2][3]
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References
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- ↑ Cohen MM, et al. (2008) Ubiquitin-Proteasome-dependent Degradation of a Mitofusin, a Critical Regulator of Mitochondrial Fusion. Mol Biol Cell 19(6):2457-64 SGD PMID 18353967
- ↑ Rapaport D, et al. (1998) Fzo1p is a mitochondrial outer membrane protein essential for the biogenesis of functional mitochondria in Saccharomyces cerevisiae. J Biol Chem 273(32):20150-5 SGD PMID 9685359
- ↑ Hermann GJ, et al. (1998) Mitochondrial fusion in yeast requires the transmembrane GTPase Fzo1p. J Cell Biol 143(2):359-73 SGD PMID 9786948
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