YOR288C

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Systematic name YOR288C
Gene name MPD1
Aliases
Feature type ORF, Verified
Coordinates Chr XV:853076..852120
Primary SGDID S000005814


Description of YOR288C: Member of the protein disulfide isomerase (PDI) family; interacts with and inhibits the chaperone activity of Cne1p; MPD1 overexpression in a pdi1 null mutant suppresses defects in Pdi1p functions such as carboxypeptidase Y maturation[1][2][3]




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References

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  1. Kimura T, et al. (2005) Interactions among Yeast Protein-Disulfide Isomerase Proteins and Endoplasmic Reticulum Chaperone Proteins Influence Their Activities. J Biol Chem 280(36):31438-41 SGD PMID 16002399
  2. Norgaard P, et al. (2001) Functional differences in yeast protein disulfide isomerases. J Cell Biol 152(3):553-62 SGD PMID 11157982
  3. Tachikawa H, et al. (1995) Isolation and characterization of a yeast gene, MPD1, the overexpression of which suppresses inviability caused by protein disulfide isomerase depletion. FEBS Lett 369(2-3):212-6 SGD PMID 7649260

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