YJR069C

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Systematic name YJR069C
Gene name HAM1
Aliases
Feature type ORF, Verified
Coordinates Chr X:569392..568799
Primary SGDID S000003830


Description of YJR069C: Conserved protein with deoxyribonucleoside triphosphate pyrophosphohydrolase activity, mediates exclusion of noncanonical purines from deoxyribonucleoside triphosphate pools; mutant is sensitive to the base analog 6-N-hydroxylaminopurine[1][2]




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References

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  1. Burgis NE and Cunningham RP (2007) Substrate Specificity of RdgB Protein, a Deoxyribonucleoside Triphosphate Pyrophosphohydrolase. J Biol Chem 282(6):3531-8 SGD PMID 17090528
  2. Noskov VN, et al. (1996) HAM1, the gene controlling 6-N-hydroxylaminopurine sensitivity and mutagenesis in the yeast Saccharomyces cerevisiae. Yeast 12(1):17-29 SGD PMID 8789257

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