YPR129W
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| Systematic name | YPR129W |
| Gene name | SCD6 |
| Aliases | LSM13 |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:792687..793736 |
| Primary SGDID | S000006333 |
Description of YPR129W: Repressor of translation initiation; binds eIF4G through its RGG domain and inhibits recruitment of the preinitiation complex; also contains an Lsm domain; may have a role in RNA processing; overproduction suppresses null mutation in clathrin heavy chain gene CHC1[1][2][3]
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References
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- ↑ Albrecht M and Lengauer T (2004) Novel Sm-like proteins with long C-terminal tails and associated methyltransferases. FEBS Lett 569(1-3):18-26 SGD PMID 15225602
- ↑ Nelson KK and Lemmon SK (1993) Suppressors of clathrin deficiency: overexpression of ubiquitin rescues lethal strains of clathrin-deficient Saccharomyces cerevisiae. Mol Cell Biol 13(1):521-32 SGD PMID 8380227
- ↑ Rajyaguru P, et al. (2012) Scd6 Targets eIF4G to Repress Translation: RGG Motif Proteins as a Class of eIF4G-Binding Proteins. Mol Cell 45(2):244-54 SGD PMID 22284680
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