YOR241W

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Systematic name YOR241W
Gene name MET7
Aliases MET23
Feature type ORF, Verified
Coordinates Chr XV:786996..788642


Description of YOR241W: Folylpolyglutamate synthetase, catalyzes extension of the glutamate chains of the folate coenzymes, required for methionine synthesis and for maintenance of mitochondrial DNA[1][2]




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References

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  1. Cherest H, et al. (2000) Polyglutamylation of folate coenzymes is necessary for methionine biosynthesis and maintenance of intact mitochondrial genome in Saccharomyces cerevisiae. J Biol Chem 275(19):14056-63 SGD PMID 10799479
  2. DeSouza L, et al. (2000) Disruption of cytoplasmic and mitochondrial folylpolyglutamate synthetase activity in Saccharomyces cerevisiae. Arch Biochem Biophys 376(2):299-312 SGD PMID 10775416

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