YNL325C

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Systematic name YNL325C
Gene name FIG4
Aliases
Feature type ORF, Verified
Coordinates Chr XIV:31377..28738


Description of YNL325C: Protein that forms a complex with Vac14p and is involved in turnover of PI3,5P2 (phosphatidylinositol 3,5-bisphosphate) after hyperosmotic shock; required for efficient mating; member of a protein family with a domain homologous to Sac1p[1][2][3]




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References

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  1. Duex JE, et al. (2006) The Vac14p-Fig4p complex acts independently of Vac7p and couples PI3,5P2 synthesis and turnover. J Cell Biol 172(5):693-704 SGD PMID 16492811
  2. Rudge SA, et al. (2004) Vacuole size control: regulation of PtdIns(3,5)P2 levels by the vacuole-associated Vac14-Fig4 complex, a PtdIns(3,5)P2-specific phosphatase. Mol Biol Cell 15(1):24-36 SGD PMID 14528018
  3. Erdman S, et al. (1998) Pheromone-regulated genes required for yeast mating differentiation. J Cell Biol 140(3):461-83 SGD PMID 9456310

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