YML057W

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Systematic name YML057W
Gene name CMP2
Aliases CNA2
Feature type ORF, Verified
Coordinates Chr XIII:160180..161994


Description of YML057W: Calcineurin A; one isoform (the other is CNA1) of the catalytic subunit of calcineurin, a Ca++/calmodulin-regulated protein phosphatase which regulates Crz1p (a stress-response transcription factor), the other calcineurin subunit is CNB1[1][2][3]




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References

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  1. Rusnak F and Mertz P (2000) Calcineurin: form and function. Physiol Rev 80(4):1483-521 SGD PMID 11015619
  2. Cyert MS (2003) Calcineurin signaling in Saccharomyces cerevisiae: how yeast go crazy in response to stress. Biochem Biophys Res Commun 311(4):1143-50 SGD PMID 14623300
  3. Garrett-Engele P, et al. (1995) Calcineurin, the Ca2+/calmodulin-dependent protein phosphatase, is essential in yeast mutants with cell integrity defects and in mutants that lack a functional vacuolar H(+)-ATPase. Mol Cell Biol 15(8):4103-14 SGD PMID 7542741

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