YML021C
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| Systematic name | YML021C |
| Gene name | UNG1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XIII:230813..229734 |
Description of YML021C: Uracil-DNA glycosylase, required for repair of uracil in DNA formed by spontaneous cytosine deamination, not required for strand-specific mismatch repair, cell-cycle regulated, expressed in late G1, localizes to mitochondria and nucleus[1][2][3][4]
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References
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- ↑ Chatterjee A and Singh KK (2001) Uracil-DNA glycosylase-deficient yeast exhibit a mitochondrial mutator phenotype. Nucleic Acids Res 29(24):4935-40 SGD PMID 11812822
- ↑ Johnston LH and Johnson AL (1995) The DNA repair genes RAD54 and UNG1 are cell cycle regulated in budding yeast but MCB promoter elements have no essential role in the DNA damage response. Nucleic Acids Res 23(12):2147-52 SGD PMID 7610042
- ↑ Crosby B, et al. (1981) Purification and characterization of a uracil-DNA glycosylase from the yeast. Saccharomyces cerevisiae. Nucleic Acids Res 9(21):5797-809 SGD PMID 7031606
- ↑ Impellizzeri KJ, et al. (1991) The spectrum of spontaneous mutations in a Saccharomyces cerevisiae uracil-DNA-glycosylase mutant limits the function of this enzyme to cytosine deamination repair. J Bacteriol 173(21):6807-10 SGD PMID 1938887
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