YLR066W

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Systematic name YLR066W
Gene name SPC3
Aliases
Feature type ORF, Verified
Coordinates Chr XII:267170..267724


Description of YLR066W: Subunit of signal peptidase complex (Spc1p, Spc2p, Spc3p, Sec11p), which catalyzes cleavage of N-terminal signal sequences of proteins targeted to the secretory pathway; homologous to mammalian SPC22/23[1][2]




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References

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  1. Meyer HA and Hartmann E (1997) The yeast SPC22/23 homolog Spc3p is essential for signal peptidase activity. J Biol Chem 272(20):13159-64 SGD PMID 9148931
  2. Fang H, et al. (1997) In addition to SEC11, a newly identified gene, SPC3, is essential for signal peptidase activity in the yeast endoplasmic reticulum. J Biol Chem 272(20):13152-8 SGD PMID 9148930

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