YKL110C

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Systematic name YKL110C
Gene name KTI12
Aliases TOT4
Feature type ORF, Verified
Coordinates Chr XI:229524..228583


Description of YKL110C: Protein that plays a role, with Elongator complex, in modification of wobble nucleosides in tRNA; involved in sensitivity to G1 arrest induced by zymocin; interacts with chromatin throughout the genome; also interacts with Cdc19p[1][2][3][4]




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References

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  1. Huang B, et al. (2005) An early step in wobble uridine tRNA modification requires the Elongator complex. RNA 11(4):424-36 SGD PMID 15769872
  2. Petrakis TG, et al. (2005) Physical and functional interaction between Elongator and the chromatin-associated Kti12 protein. J Biol Chem 280(20):19454-60 SGD PMID 15772087
  3. Fichtner L, et al. (2002) Protein interactions within Saccharomyces cerevisiae Elongator, a complex essential for Kluyveromyces lactis zymocicity. Mol Microbiol 45(3):817-26 SGD PMID 12139626
  4. Butler AR, et al. (1994) Two Saccharomyces cerevisiae genes which control sensitivity to G1 arrest induced by Kluyveromyces lactis toxin. Mol Cell Biol 14(9):6306-16 SGD PMID 8065362

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