YHR194W

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Systematic name YHR194W
Gene name MDM31
Aliases
Feature type ORF, Verified
Coordinates Chr VIII:488657..490396


Description of YHR194W: Mitochondrial inner membrane protein with similarity to Mdm32p, required for normal mitochondrial morphology and inheritance; interacts genetically with MMM1, MDM10, MDM12, and MDM34[1]




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Community Commentary

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Other

mitochondrial biogenesis

Mdm31p (as well as Mdm32p) seems to play a role in regulation of mitochondrial cation homeostasis and mitochondrial volume. [2] [3]




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References

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  1. Dimmer KS, et al. (2005) Mdm31 and Mdm32 are inner membrane proteins required for maintenance of mitochondrial shape and stability of mitochondrial DNA nucleoids in yeast. J Cell Biol 168(1):103-15 SGD PMID 15631992
  2. Kucejova B, et al. (2005) A screen for nigericin-resistant yeast mutants revealed genes controlling mitochondrial volume and mitochondrial cation homeostasis. Genetics 171(2):517-26 SGD PMID 16020778
  3. submitted by Lubomir Tomaska on 2005-12-21

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