YML036W
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| Systematic name | YML036W |
| Gene name | CGI121 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XIII:205642..206293 |
| Primary SGDID | S000004500 |
Description of YML036W: Component of the EKC/KEOPS complex with Bud32p, Kae1p, Pcc1p, and Gon7p; EKC/KEOPS complex is required for t6A tRNA modification and may have roles in telomere maintenance and transcription; Cgi121p is dispensable for tRNA modification[1][2][3]
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References
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- ↑ Downey M, et al. (2006) A genome-wide screen identifies the evolutionarily conserved KEOPS complex as a telomere regulator. Cell 124(6):1155-68 SGD PMID 16564010
- ↑ Kisseleva-Romanova E, et al. (2006) Yeast homolog of a cancer-testis antigen defines a new transcription complex. EMBO J 25(15):3576-85 SGD PMID 16874308
- ↑ Srinivasan M, et al. (2011) The highly conserved KEOPS/EKC complex is essential for a universal tRNA modification, t6A. EMBO J 30(5):873-81 SGD PMID 21183954
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