YGR216C
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| Systematic name | YGR216C |
| Gene name | GPI1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:924467..922638 |
Description of YGR216C: Membrane protein involved in the synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the synthesis of glycosylphosphatidylinositol (GPI) anchors; human and mouse GPI1p are functional homologs[1][2][3][4]
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References
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- ↑ Watanabe R, et al. (1998) The first step of glycosylphosphatidylinositol biosynthesis is mediated by a complex of PIG-A, PIG-H, PIG-C and GPI1. EMBO J 17(4):877-85 SGD PMID 9463366
- ↑ Leidich SD, et al. (1994) A conditionally lethal yeast mutant blocked at the first step in glycosyl phosphatidylinositol anchor synthesis. J Biol Chem 269(14):10193-6 SGD PMID 8144596
- ↑ Leidich SD and Orlean P (1996) Gpi1, a Saccharomyces cerevisiae protein that participates in the first step in glycosylphosphatidylinositol anchor synthesis. J Biol Chem 271(44):27829-37 SGD PMID 8910381
- ↑ Tiede A, et al. (1998) Human and mouse Gpi1p homologues restore glycosylphosphatidylinositol membrane anchor biosynthesis in yeast mutants. Biochem J 334 ( Pt 3)():609-16 SGD PMID 9729469
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