YOR160W

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Systematic name YOR160W
Gene name MTR10
Aliases KAP111
Feature type ORF, Verified
Coordinates Chr XV:633839..636757
Primary SGDID S000005686


Description of YOR160W: Nuclear import receptor, mediates the nuclear localization of proteins involved in mRNA-nucleus export; promotes dissociation of mRNAs from the nucleus-cytoplasm mRNA shuttling protein Npl3p; required for retrograde import of mature tRNAs[1][2][3][4]




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References

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  1. Jump up Murthi A, et al. (2010) Regulation of tRNA Bidirectional Nuclear-Cytoplasmic Trafficking in Saccharomyces cerevisiae. Mol Biol Cell 21(4):639-49 SGD PMID 20032305
  2. Jump up Pemberton LF, et al. (1997) A distinct and parallel pathway for the nuclear import of an mRNA-binding protein. J Cell Biol 139(7):1645-53 SGD PMID 9412460
  3. Jump up Senger B, et al. (1998) Mtr10p functions as a nuclear import receptor for the mRNA-binding protein Npl3p. EMBO J 17(8):2196-207 SGD PMID 9545233
  4. Jump up Windgassen M, et al. (2004) Yeast shuttling SR proteins Npl3p, Gbp2p, and Hrb1p are part of the translating mRNPs, and Npl3p can function as a translational repressor. Mol Cell Biol 24(23):10479-91 SGD PMID 15542855

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