YOR076C
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| Systematic name | YOR076C |
| Gene name | SKI7 |
| Aliases | YOR29-27 |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:471620..469377 |
| Primary SGDID | S000005602 |
Description of YOR076C: Coupling protein that mediates interactions between the Ski complex and the cytoplasmic exosome during 3'-5' RNA degradation; eRF3-like domain targets nonstop mRNA for degradation; null mutants have superkiller phenotype[1][2][3][4][5]
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Community Commentary
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References
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- ↑ Araki Y, et al. (2001) Ski7p G protein interacts with the exosome and the Ski complex for 3'-to-5' mRNA decay in yeast. EMBO J 20(17):4684-93 SGD PMID 11532933
- ↑ Benard L, et al. (1999) The ski7 antiviral protein is an EF1-alpha homolog that blocks expression of non-Poly(A) mRNA in Saccharomyces cerevisiae. J Virol 73(4):2893-900 SGD PMID 10074137
- ↑ Wang L, et al. (2005) Domain interactions within the Ski2/3/8 complex and between the Ski complex and Ski7p. RNA 11(8):1291-302 SGD PMID 16043509
- ↑ van Hoof A, et al. (2000) Function of the ski4p (Csl4p) and Ski7p proteins in 3'-to-5' degradation of mRNA. Mol Cell Biol 20(21):8230-43 SGD PMID 11027292
- ↑ van Hoof A, et al. (2002) Exosome-mediated recognition and degradation of mRNAs lacking a termination codon. Science 295(5563):2262-4 SGD PMID 11910110
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