YOR232W
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| Systematic name | YOR232W |
| Gene name | MGE1 |
| Aliases | GRPE, YGE1 |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:774573..775259 |
| Primary SGDID | S000005758 |
Description of YOR232W: Mitochondrial matrix cochaperone, acts as a nucleotide release factor for Ssc1p in protein translocation and folding; also acts as cochaperone for Ssq1p in folding of Fe-S cluster proteins; homolog of E. coli GrpE[1][2][3][4][5][6]
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Community Commentary
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References
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- ↑ Bolliger L, et al. (1994) A mitochondrial homolog of bacterial GrpE interacts with mitochondrial hsp70 and is essential for viability. EMBO J 13(8):1998-2006 SGD PMID 8168496
- ↑ Deloche O and Georgopoulos C (1996) Purification and biochemical properties of Saccharomyces cerevisiae's Mge1p, the mitochondrial cochaperone of Ssc1p. J Biol Chem 271(39):23960-6 SGD PMID 8798629
- ↑ Ikeda E, et al. (1994) YGE1 is a yeast homologue of Escherichia coli grpE and is required for maintenance of mitochondrial functions. FEBS Lett 339(3):265-8 SGD PMID 8112465
- ↑ Laloraya S, et al. (1994) A role for a eukaryotic GrpE-related protein, Mge1p, in protein translocation. Proc Natl Acad Sci U S A 91(14):6481-5 SGD PMID 8022808
- ↑ Miao B, et al. (1997) Mge1 functions as a nucleotide release factor for Ssc1, a mitochondrial Hsp70 of Saccharomyces cerevisiae. J Mol Biol 265(5):541-52 SGD PMID 9048947
- ↑ Schmidt S, et al. (2001) The two mitochondrial heat shock proteins 70, Ssc1 and Ssq1, compete for the cochaperone Mge1. J Mol Biol 313(1):13-26 SGD PMID 11601843
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