YGL195W

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Systematic name YGL195W
Gene name GCN1
Aliases AAS103, NDR1
Feature type ORF, Verified
Coordinates Chr VII:131531..139549
Primary SGDID S000003163


Description of YGL195W: Positive regulator of the Gcn2p kinase activity, forms a complex with Gcn20p; proposed to stimulate Gcn2p activation by an uncharged tRNA[1][2]




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References

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  1. Garcia-Barrio M, et al. (2000) Association of GCN1-GCN20 regulatory complex with the N-terminus of eIF2alpha kinase GCN2 is required for GCN2 activation. EMBO J 19(8):1887-99 SGD PMID 10775272
  2. Kubota H, et al. (2001) Budding yeast GCN1 binds the GI domain to activate the eIF2alpha kinase GCN2. J Biol Chem 276(20):17591-6 SGD PMID 11350982

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