YGL247W

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Systematic name YGL247W
Gene name BRR6
Aliases
Feature type ORF, Verified
Coordinates Chr VII:36933..37526
Primary SGDID S000003216


Description of YGL247W: Essential nuclear envelope integral membrane protein required for nuclear envelope morphology, nuclear pore complex localization, nuclear export; exhibits synthetic lethal genetic interactions with genes involved in lipid metabolism[1][2]




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References

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  1. Hodg CA, et al. (2010) Integral membrane proteins Brr6 and Apq12 link assembly of the nuclear pore complex to lipid homeostasis in the endoplasmic reticulum. J Cell Sci 123(Pt 1):141-151 SGD PMID 20016074
  2. de Bruyn Kops A and Guthrie C (2001) An essential nuclear envelope integral membrane protein, Brr6p, required for nuclear transport. EMBO J 20(15):4183-93 SGD PMID 11483521

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