YMR037C
Share your knowledge...Edit this entry!
Systematic name | YMR037C | |
Gene name | MSN2 | |
Aliases | ||
Feature type | ORF, Verified | |
Coordinates | Chr XIII:346516..344402 | |
Don't edit this box! It's automatically regenerated, and edits will be lost when the update script runs. |
Description of YMR037C: Transcriptional activator related to Msn4p; activated in stress conditions, which results in translocation from the cytoplasm to the nucleus; binds DNA at stress response elements of responsive genes, inducing gene expression[1][2]
Community Commentary
About Community Commentary. Please share your knowledge!
Interactions
Regulatory
Regulatory interaction with YBL064c
YBL064c is up regulated by Msn2p/Msn4p during glucose exhaustion (cells grown in respiratory carbon sources, such as glycerol / ethanol). Exogenously added cAMP represses the induction of YBL064c mRNA expression even in respiratory conditions. [3] [4]
References
See Help:References on how to add references
- ↑ Gorner W, et al. (1998) Nuclear localization of the C2H2 zinc finger protein Msn2p is regulated by stress and protein kinase A activity. Genes Dev 12(4):586-97 SGD PMID 9472026
- ↑ Martinez-Pastor MT, et al. (1996) The Saccharomyces cerevisiae zinc finger proteins Msn2p and Msn4p are required for transcriptional induction through the stress response element (STRE). EMBO J 15(9):2227-35 SGD PMID 8641288
- ↑ Monteiro G, et al. (2002) Regulation of mitochondrial thioredoxin peroxidase I expression by two different pathways: one dependent on cAMP and the other on heme. Free Radic Biol Med 32(3):278-88 SGD PMID 11827753
- ↑ submitted by Gisele Monteiro on 2003-03-31
See Help:Categories on how to add the wiki page for this gene to a Category