YKL216W
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| Systematic name | YKL216W |
| Gene name | URA1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XI:25215..26159 |
| Primary SGDID | S000001699 |
Description of YKL216W: Dihydroorotate dehydrogenase, catalyzes the fourth enzymatic step in the de novo biosynthesis of pyrimidines, converting dihydroorotic acid into orotic acid[1][2][3]
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Community Commentary
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Other
Gene Origin
Horizontally transferred from lactic acid bacteria [4] [5]
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References
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- ↑ Guerry-Kopecko P and Wickner RB (1980) Cloning of the URA1 gene of Saccharomyces cerevisiae. J Bacteriol 143(3):1530-3 SGD PMID 6251032
- ↑ Lacroute F (1968) Regulation of pyrimidine biosynthesis in Saccharomyces cerevisiae. J Bacteriol 95(3):824-32 SGD PMID 5651325
- ↑ Vorisek J, et al. (2002) Enzymatic activities of Ura2 and Ura1 proteins (aspartate carbamoyltransferase and dihydro-orotate dehydrogenase) are present in both isolated membranes and cytoplasm of Saccharomyces cerevisiae. Yeast 19(5):449-57 SGD PMID 11921093
- ↑ Hall C, et al. (2005) Contribution of horizontal gene transfer to the evolution of Saccharomyces cerevisiae. Eukaryot Cell 4(6):1102-15 SGD PMID 15947202
- ↑ submitted by Charles Hall on 2006-06-09
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