YBR270C
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| Systematic name | YBR270C |
| Gene name | BIT2 |
| Aliases | |
| Feature type | ORF, Uncharacterized |
| Coordinates | Chr II:744393..742756 |
| Primary SGDID | S000000474 |
Description of YBR270C: Subunit of TORC2, a membrane-associated complex that regulates actin cytoskeletal dynamics during polarized growth and cell wall integrity; interacts with Slm1p and Slm2p, homologous PH domain-containing TORC2 substrates; similar to Bit61p[1][2][3][4]
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References
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- ↑ De Virgilio C and Loewith R (2006) Cell growth control: little eukaryotes make big contributions. Oncogene 25(48):6392-415 SGD PMID 17041625
- ↑ Fadri M, et al. (2005) The pleckstrin homology domain proteins Slm1 and Slm2 are required for actin cytoskeleton organization in yeast and bind phosphatidylinositol-4,5-bisphosphate and TORC2. Mol Biol Cell 16(4):1883-900 SGD PMID 15689497
- ↑ Rohde JR, et al. (2008) Nutritional control via Tor signaling in Saccharomyces cerevisiae. Curr Opin Microbiol 11(2):153-60 SGD PMID 18396450
- ↑ Schmidt A, et al. (1996) TOR2 is required for organization of the actin cytoskeleton in yeast. Proc Natl Acad Sci U S A 93(24):13780-5 SGD PMID 8943012
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