YOR175C

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Systematic name YOR175C
Gene name ALE1
Aliases LCA1, LPT1, SLC4
Feature type ORF, Verified
Coordinates Chr XV:661675..659816
Primary SGDID S000005701


Description of YOR175C: Lysophospholipid acyltransferase, partially redundant with Slc1p; part of MBOAT family of membrane-bound O-acyltransferases; key component of Lands cycle; may have role in fatty acid exchange at sn-2 position of mature glycerophospholipids[1][2][3][4][5]




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References

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  1. Fleischer TC, et al. (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307 SGD PMID 16702403
  2. Benghezal M, et al. (2007) SLC1 and SLC4 Encode Partially Redundant Acyl-Coenzyme A 1-Acylglycerol-3-phosphate O-Acyltransferases of Budding Yeast. J Biol Chem 282(42):30845-55 SGD PMID 17675291
  3. Riekhof WR, et al. (2007) Identification and characterization of the major lysophosphatidylethanolamine acyltransferase in Saccharomyces cerevisiae. J Biol Chem 282(39):28344-52 SGD PMID 17652094
  4. Jain S, et al. (2007) Identification of a Novel Lysophospholipid Acyltransferase in Saccharomyces cerevisiae. J Biol Chem 282(42):30562-9 SGD PMID 17726007
  5. Chen Q, et al. (2007) The yeast acylglycerol acyltransferase LCA1 is a key component of Lands cycle for phosphatidylcholine turnover. FEBS Lett 581(28):5511-6 SGD PMID 17996202

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