YNL329C
Share your knowledge...Edit this entry! <protect>
| Systematic name | YNL329C |
| Gene name | PEX6 |
| Aliases | PAS8 |
| Feature type | ORF, Verified |
| Coordinates | Chr XIV:22633..19541 |
| Primary SGDID | S000005273 |
Description of YNL329C: AAA-peroxin that heterodimerizes with AAA-peroxin Pex1p and participates in the recycling of peroxisomal signal receptor Pex5p from the peroxisomal membrane to the cystosol[1][2][3]
</protect>
Community Commentary
About Community Commentary. Please share your knowledge!
Protein Details
Other Protein Details
Other Topic: Homology
Homology was found, at the sequence and domain-composition level, between several components of the Peroxisomal protein import machinery and components of the Endoplasmic Reticulum Associated Decay (ERAD) pathway. This suggests a common evolutionary origin for both systems and a similar mechanism of action. The homology relationships can be stablished between Pex1,Pex6 and cdc48; Pex2 and Hrd1; Pex4 and Ubc1; and Pex5 and Hrd3. [4] [5]
<protect>
References
See Help:References on how to add references
- ↑ Voorn-Brouwer T, et al. (1993) Sequence of the PAS8 gene, the product of which is essential for biogenesis of peroxisomes in Saccharomyces cerevisiae. Biochim Biophys Acta 1216(2):325-8 SGD PMID 8241279
- ↑ Birschmann I, et al. (2005) Structural and functional analysis of the interaction of the AAA-peroxins Pex1p and Pex6p. FEBS J 272(1):47-58 SGD PMID 15634331
- ↑ Platta HW, et al. (2005) Functional role of the AAA peroxins in dislocation of the cycling PTS1 receptor back to the cytosol. Nat Cell Biol 7(8):817-22 SGD PMID 16007078
- ↑ Gabaldon T, et al. (2006) Origin and evolution of the peroxisomal proteome. Biol Direct 1():8 SGD PMID 16556314
- ↑ submitted by Toni Gabaldon on 2006-04-12
See Help:Categories on how to add the wiki page for this gene to a Category </protect>
