YDR495C
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| Systematic name | YDR495C |
| Gene name | VPS3 |
| Aliases | PEP6, VPL3, VPT17 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:1441143..1438108 |
| Primary SGDID | S000002903 |
Description of YDR495C: Component of CORVET tethering complex; cytoplasmic protein required for the sorting and processing of soluble vacuolar proteins, acidification of the vacuolar lumen, and assembly of the vacuolar H+-ATPase[1][2][3][4]
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References
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- ↑ Rothman JH, et al. (1989) Acidification of the lysosome-like vacuole and the vacuolar H+-ATPase are deficient in two yeast mutants that fail to sort vacuolar proteins. J Cell Biol 109(1):93-100 SGD PMID 2526133
- ↑ Robinson JS, et al. (1988) Protein sorting in Saccharomyces cerevisiae: isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolases. Mol Cell Biol 8(11):4936-48 SGD PMID 3062374
- ↑ Raymond CK, et al. (1990) Molecular analysis of the yeast VPS3 gene and the role of its product in vacuolar protein sorting and vacuolar segregation during the cell cycle. J Cell Biol 111(3):877-92 SGD PMID 2202738
- ↑ Peplowska K, et al. (2007) The CORVET Tethering Complex Interacts with the Yeast Rab5 Homolog Vps21 and Is Involved in Endo-Lysosomal Biogenesis. Dev Cell 12(5):739-50 SGD PMID 17488625
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