YCR075C
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Systematic name | YCR075C |
Gene name | ERS1 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr III:248812..248030 |
Primary SGDID | S000000671 |
Description of YCR075C: Protein with similarity to human cystinosin, which is a H(+)-driven transporter involved in L-cystine export from lysosomes and implicated in the disease cystinosis; contains seven transmembrane domains[1][2]
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References
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- ↑ Hardwick KG and Pelham HR (1990) ERS1 a seven transmembrane domain protein from Saccharomyces cerevisiae. Nucleic Acids Res 18(8):2177 SGD PMID 2186379
- ↑ Kalatzis V, et al. (2001) Cystinosin, the protein defective in cystinosis, is a H(+)-driven lysosomal cystine transporter. EMBO J 20(21):5940-9 SGD PMID 11689434
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