YKL178C

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Systematic name YKL178C
Gene name STE3
Aliases DAF2
Feature type ORF, Verified
Coordinates Chr XI:114632..113220
Primary SGDID S000001661


Description of YKL178C: Receptor for a factor receptor, transcribed in alpha cells and required for mating by alpha cells, couples to MAP kinase cascade to mediate pheromone response; ligand bound receptors are endocytosed and recycled to the plasma membrane; GPCR[1][2]




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References

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  1. Chen L and Davis NG (2000) Recycling of the yeast a-factor receptor. J Cell Biol 151(3):731-8 SGD PMID 11062272
  2. Hagen DC, et al. (1986) Evidence the yeast STE3 gene encodes a receptor for the peptide pheromone a factor: gene sequence and implications for the structure of the presumed receptor. Proc Natl Acad Sci U S A 83(5):1418-22 SGD PMID 3006051

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