Difference between revisions of "YEL029C"
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− | '''Description of YEL029C:''' | + | '''Description of YEL029C:''' Putative pyridoxal kinase, key enzyme in vitamin B6 metabolism; involved in maintaining levels of pyridoxal 5'-phosphate, the active form of vitamin B6; required for genome integrity; homolog of E. coli PdxK; involved in bud-site selection<ref name='S000124890'>Tanaka T, et al. (2005) Evolution of vitamin B6 (pyridoxine) metabolism by gain and loss of genes. Mol Biol Evol 22(2):243-50 {{SGDpaper|S000124890}} PMID 15483325</ref><ref name='S000123841'>Kanellis P, et al. (2007) A screen for suppressors of gross chromosomal rearrangements identifies a conserved role for PLP in preventing DNA lesions. PLoS Genet 3(8):e134 {{SGDpaper|S000123841}} PMID 17696614</ref><ref name='S000114270'>Askree SH, et al. (2004) A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Proc Natl Acad Sci U S A 101(23):8658-63 {{SGDpaper|S000114270}} PMID 15161972</ref><ref name='S000061390'>Ni L and Snyder M (2001) A genomic study of the bipolar bud site selection pattern in Saccharomyces cerevisiae. Mol Biol Cell 12(7):2147-70 |
{{SGDpaper|S000061390}} PMID 11452010</ref> | {{SGDpaper|S000061390}} PMID 11452010</ref> | ||
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Revision as of 13:05, 6 December 2007
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Systematic name | YEL029C |
Gene name | BUD16 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr V:97796..96858 |
Primary SGDID | S000000755 |
Description of YEL029C: Putative pyridoxal kinase, key enzyme in vitamin B6 metabolism; involved in maintaining levels of pyridoxal 5'-phosphate, the active form of vitamin B6; required for genome integrity; homolog of E. coli PdxK; involved in bud-site selection[1][2][3][4]
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References
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- ↑ Tanaka T, et al. (2005) Evolution of vitamin B6 (pyridoxine) metabolism by gain and loss of genes. Mol Biol Evol 22(2):243-50 SGD PMID 15483325
- ↑ Kanellis P, et al. (2007) A screen for suppressors of gross chromosomal rearrangements identifies a conserved role for PLP in preventing DNA lesions. PLoS Genet 3(8):e134 SGD PMID 17696614
- ↑ Askree SH, et al. (2004) A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Proc Natl Acad Sci U S A 101(23):8658-63 SGD PMID 15161972
- ↑ Ni L and Snyder M (2001) A genomic study of the bipolar bud site selection pattern in Saccharomyces cerevisiae. Mol Biol Cell 12(7):2147-70 SGD PMID 11452010
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