Difference between revisions of "S000000152"

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#REDIRECT [[YBL056W]]
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YBL056W YBL056W]
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''PTC3 ''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||'' ''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|nowrap| Chr II:113765..115171
 
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'''Description of {{PAGENAME}}:''' Type 2C protein phosphatase; dephosphorylates Hog1p (see also Ptc2p) to limit maximal kinase activity induced by osmotic stress; dephosphorylates T169 phosphorylated Cdc28p (see also Ptc2p); role in DNA checkpoint inactivation<ref name='S000073153'>Leroy C, et al. (2003) PP2C phosphatases Ptc2 and Ptc3 are required for DNA checkpoint inactivation after a double-strand break. Mol Cell 11(3):827-35 {{SGDpaper|S000073153}} PMID 12667463</ref><ref name='S000071972'>Young C, et al. (2002) Role of Ptc2 type 2C Ser/Thr phosphatase in yeast high-osmolarity glycerol pathway inactivation. Eukaryot Cell 1(6):1032-40 {{SGDpaper|S000071972}} PMID 12477803</ref><ref name='S000059233'>Warmka J, et al. (2001) Ptc1, a type 2C Ser/Thr phosphatase, inactivates the HOG pathway by dephosphorylating the mitogen-activated protein kinase Hog1. Mol Cell Biol 21(1):51-60 {{SGDpaper|S000059233}} PMID 11113180</ref><ref name='S000046820'>Maeda T, et al. (1993) Mutations in a protein tyrosine phosphatase gene (PTP2) and a protein serine/threonine phosphatase gene (PTC1) cause a synthetic growth defect in Saccharomyces cerevisiae. Mol Cell Biol 13(9):5408-17 {{SGDpaper|S000046820}} PMID 8395005</ref><ref name='S000040841'>Cheng A, et al. (1999) Dephosphorylation of cyclin-dependent kinases by type 2C protein phosphatases. Genes Dev 13(22):2946-57
 
{{SGDpaper|S000040841}} PMID 10580002</ref>
 
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==Community Commentary==
 
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==References==
 
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Latest revision as of 08:46, 27 February 2007

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