Difference between revisions of "YOR204W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl? | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005730 YOR204W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''DED1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''DED1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr XV:722912..724726 | |nowrap| Chr XV:722912..724726 | ||
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000005730 | ||
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| − | '''Description of | + | '''Description of YOR204W:''' ATP-dependent DEAD (Asp-Glu-Ala-Asp)-box RNA helicase, required for translation initiation of all yeast mRNAs; mutations in human DEAD-box DBY are a frequent cause of male infertility<ref name='S000080391'>Johnstone O, et al. (2005) Belle is a Drosophila DEAD-box protein required for viability and in the germ line. Dev Biol 277(1):92-101 {{SGDpaper|S000080391}} PMID 15572142</ref><ref name='S000060379'>Noueiry AO, et al. (2000) A mutant allele of essential, general translation initiation factor DED1 selectively inhibits translation of a viral mRNA. Proc Natl Acad Sci U S A 97(24):12985-90 {{SGDpaper|S000060379}} PMID 11069307</ref><ref name='S000048410'>Iost I, et al. (1999) Ded1p, a DEAD-box protein required for translation initiation in Saccharomyces cerevisiae, is an RNA helicase. J Biol Chem 274(25):17677-83 |
{{SGDpaper|S000048410}} PMID 10364207</ref> | {{SGDpaper|S000048410}} PMID 10364207</ref> | ||
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 07:46, 27 February 2007
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| Systematic name | YOR204W |
| Gene name | DED1 |
| Aliases | SPP81 |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:722912..724726 |
| Primary SGDID | S000005730 |
Description of YOR204W: ATP-dependent DEAD (Asp-Glu-Ala-Asp)-box RNA helicase, required for translation initiation of all yeast mRNAs; mutations in human DEAD-box DBY are a frequent cause of male infertility[1][2][3]
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References
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- ↑ Johnstone O, et al. (2005) Belle is a Drosophila DEAD-box protein required for viability and in the germ line. Dev Biol 277(1):92-101 SGD PMID 15572142
- ↑ Noueiry AO, et al. (2000) A mutant allele of essential, general translation initiation factor DED1 selectively inhibits translation of a viral mRNA. Proc Natl Acad Sci U S A 97(24):12985-90 SGD PMID 11069307
- ↑ Iost I, et al. (1999) Ded1p, a DEAD-box protein required for translation initiation in Saccharomyces cerevisiae, is an RNA helicase. J Biol Chem 274(25):17677-83 SGD PMID 10364207
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