Difference between revisions of "YOL112W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl? | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005472 YOL112W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''MSB4 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''MSB4 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr XV:106710..108188 | |nowrap| Chr XV:106710..108188 | ||
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000005472 | ||
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<br> | <br> | ||
| − | '''Description of | + | '''Description of YOL112W:''' GTPase-activating protein of the Ras superfamily that acts primarily on Sec4p, localizes to the bud site and bud tip, has similarity to Msb3p; msb3 msb4 double mutation causes defects in secretion and actin organization<ref name='S000073833'>Gao XD, et al. (2003) The GAP activity of Msb3p and Msb4p for the Rab GTPase Sec4p is required for efficient exocytosis and actin organization. J Cell Biol 162(4):635-46 {{SGDpaper|S000073833}} PMID 12913108</ref><ref name='S000062162'>Albert S and Gallwitz D (2000) Msb4p, a protein involved in Cdc42p-dependent organization of the actin cytoskeleton, is a Ypt/Rab-specific GAP. Biol Chem 381(5-6):453-6 {{SGDpaper|S000062162}} PMID 10937877</ref><ref name='S000040830'>Bi E, et al. (2000) Identification of novel, evolutionarily conserved Cdc42p-interacting proteins and of redundant pathways linking Cdc24p and Cdc42p to actin polarization in yeast. Mol Biol Cell 11(2):773-93 |
{{SGDpaper|S000040830}} PMID 10679030</ref> | {{SGDpaper|S000040830}} PMID 10679030</ref> | ||
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 07:46, 27 February 2007
Share your knowledge...Edit this entry! <protect>
| Systematic name | YOL112W |
| Gene name | MSB4 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:106710..108188 |
| Primary SGDID | S000005472 |
Description of YOL112W: GTPase-activating protein of the Ras superfamily that acts primarily on Sec4p, localizes to the bud site and bud tip, has similarity to Msb3p; msb3 msb4 double mutation causes defects in secretion and actin organization[1][2][3]
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References
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- ↑ Gao XD, et al. (2003) The GAP activity of Msb3p and Msb4p for the Rab GTPase Sec4p is required for efficient exocytosis and actin organization. J Cell Biol 162(4):635-46 SGD PMID 12913108
- ↑ Albert S and Gallwitz D (2000) Msb4p, a protein involved in Cdc42p-dependent organization of the actin cytoskeleton, is a Ypt/Rab-specific GAP. Biol Chem 381(5-6):453-6 SGD PMID 10937877
- ↑ Bi E, et al. (2000) Identification of novel, evolutionarily conserved Cdc42p-interacting proteins and of redundant pathways linking Cdc24p and Cdc42p to actin polarization in yeast. Mol Biol Cell 11(2):773-93 SGD PMID 10679030
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