Difference between revisions of "YNL223W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl? | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005167 YNL223W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''ATG4 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''ATG4 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr XIV:227371..228855 | |nowrap| Chr XIV:227371..228855 | ||
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000005167 | ||
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<br> | <br> | ||
| − | '''Description of | + | '''Description of YNL223W:''' Cysteine protease required for autophagy; cleaves Atg8p to a form required for autophagosome and Cvt vesicle generation; mediates attachment of autophagosomes to microtubules through interactions with Tub1p and Tub2p<ref name='S000059897'>Kirisako T, et al. (2000) The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway. J Cell Biol 151(2):263-76 {{SGDpaper|S000059897}} PMID 11038174</ref><ref name='S000051835'>Tsukada M and Ohsumi Y (1993) Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett 333(1-2):169-74 {{SGDpaper|S000051835}} PMID 8224160</ref><ref name='S000046683'>Lang T, et al. (1998) Aut2p and Aut7p, two novel microtubule-associated proteins are essential for delivery of autophagic vesicles to the vacuole. EMBO J 17(13):3597-607 |
{{SGDpaper|S000046683}} PMID 9649430</ref> | {{SGDpaper|S000046683}} PMID 9649430</ref> | ||
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 08:46, 27 February 2007
Share your knowledge...Edit this entry! <protect>
| Systematic name | YNL223W |
| Gene name | ATG4 |
| Aliases | APG4, AUT2 |
| Feature type | ORF, Verified |
| Coordinates | Chr XIV:227371..228855 |
| Primary SGDID | S000005167 |
Description of YNL223W: Cysteine protease required for autophagy; cleaves Atg8p to a form required for autophagosome and Cvt vesicle generation; mediates attachment of autophagosomes to microtubules through interactions with Tub1p and Tub2p[1][2][3]
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Contents
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References
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- ↑ Kirisako T, et al. (2000) The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway. J Cell Biol 151(2):263-76 SGD PMID 11038174
- ↑ Tsukada M and Ohsumi Y (1993) Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett 333(1-2):169-74 SGD PMID 8224160
- ↑ Lang T, et al. (1998) Aut2p and Aut7p, two novel microtubule-associated proteins are essential for delivery of autophagic vesicles to the vacuole. EMBO J 17(13):3597-607 SGD PMID 9649430
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